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Description
It's worth noting that when GLP-1 receptor agonists are used alongside insulin or sulfonylureas, there is an increased risk of hypoglycaemia, and dose adjustments of these medications may be required

These medications appear to dial down activity in the brain's reward pathways, the same circuits that make alcohol feel rewarding

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Severity ranges from mild queasiness to more significant stomach upset, though severe nausea is uncommon

Orforglipron (Foundayo) approved April 2026, the first once-daily GLP-1 pill with no food or water restrictions

Liraglutide (Victoza) injection [package insert]
