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In women with polycystic ovary syndrome, weight loss from GLP-1 treatment reduces elevated testosterone levels by approximately 33 percent, which is therapeutically beneficial because excess testosterone drives unwanted symptoms like acne and hirsutism in PCOS

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2 Researchers have been able to show through many studies that GLP-1 indirectly works in the liver by inhibiting glucagon secretion by pancreatic alpha-cells, thereby inhibiting gluconeogenesis and glycogenolysis, thus decreasing hepatic glucose production