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However, its direct therapeutic application is limited by its rapid inactivation via the enzyme dipeptidyl peptidase 4 (DPP-4), which cleaves GLP-1 (736) at position 8 to generate the inactive metabolite GLP-1 (936), resulting in a plasma half-life of only 1 to 2 min

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118 , 6887 (2016) Venkatakrishnan, A

Clinical Research Context: What the Studies Actually Show Published clinical trials evaluated FDA-approved formulations

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