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The trial, called SELECT, was conducted in 41 countries with more than 17,000 people who were overweight or obese and at high cardiovascular risk but who didnt have diabetes

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This year, Lilly has been releasing the results of clinical studies finding that orforglipron is safe and efficacious in patients with obesity or type 2 diabetes

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Mean TTR decreased by 2.1% (95% CI, -3.7% to -0.6%

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10.26355/eurrev_202107_26395 79 LopezL

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The mechanism involves glucose-dependent insulin secretion, meaning insulin release occurs primarily when blood glucose levels are elevated, thereby reducing the risk of hypoglycemia when used as monotherapy

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Diabetes also is associated with more rapid progression of Parkinsons symptoms in people who have both diseases

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