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Recent studies suggest that tirzepatide, a dual glucose-dependent insulinotropic-peptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA), has significant weight loss effects

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This intentional formulation directly addresses the critical need for muscle preservation for individuals on GLP-1 therapies

I am pleased to see, however, that NICE recognises that some ethnicities may be prone to obesity-related complications at a lower BMI and so have lowered the referral threshold by 2.5kg/m2 for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds

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