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Acta estimulando de forma fisiolgica el GLP-1, una hormona clave en la regulacin del apetito, ayudando a aumentar la saciedad y reducir la ingesta calrica

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Conversely, long-acting GLP-1 RAs are associated with more pronounced increases in mean 24-h HR

Insulin resistance and chronic hyperglycemia cause a cascade of pathological events in the brain, including neuroinflammation, impaired neurotransmitter systems and energy metabolism, oxidative stress, and vascular pathologies that ultimately lead to neurodegeneration, loss of synaptic plasticity, brain aging, cognitive impairment, and dementia

Lifestyle interventions remain the cornerstone of obesity management in older adults, with emphasis on resistance training for muscle strength and bone mineral density preservation