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Unlike FDA-approved drugs, compounded medications are not reviewed by the FDA for safety, effectiveness, or quality

In 731 patients with HFpEF and obesity, tirzepatide demonstrated a 38% reduction in the composite endpoint of cardiovascular death or worsening heart failure events (HR 0.62, 95% CI 0.410.95), representing one of the most significant treatment effects ever observed in HFpEF [90]

The question isn't whether psychiatrists should treat metabolic dysfunction

In SURMOUNT-3, 600 participants are randomized to receive either tirzepatide at the maximally tolerated dose or placebo following a structured intensive 12-week lifestyle intervention

Men frequently report that the most life-changing benefit of tirzepatide is not how they look

Easley C
