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Semaglutide may cause side effects, including gastrointestinal symptoms and other potential risks

Next steps: FDA decision (REDEFINE-1 & 2) expected late 2026 REDEFINE-11 (2.4/2.4 mg) readout in H1 2027 Higher-dose Phase 3 initiation planned H2 2026 Why It Matters: The obesity market is now a high-efficacy battleground, with GLP-1 and dual incretin therapies redefining standards of care

and Shanshan et al., indicating that higher baseline adiposity may amplify the effectiveness of semaglutide in reducing fat markers and enhancing glycemic control

While experts say the new dose could benefit patients who need additional weight loss, they caution that higher doses may increase side effects

Compounded semaglutide and compounded tirzepatide are different products

You may experience some swelling or bruising after the procedure, but most patients can resume their normal activities within a day or two