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JAMA 2022;327:13850

Ozempic carries a boxed warning and is contraindicated for patients with a personal or family history of medullary thyroid carcinoma

Ask about the specific medication being consideredwhether semaglutide (Wegovy) or tirzepatide (Zepbound), which are FDA-approved for chronic weight managementand how your cholecystectomy history might influence the choice

Retatrutide appears to push the boundaries further with its third receptor target

10.1007/BF02427280

This makes them much better suited to treatment compliance than addiction therapies which require daily administration (and it should be noted that several longer acting formulations of existing SUD medications are coming to market as well)