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A small amount of bleeding or clear fluid is normal and requires only gentle pressure with a clean tissue for 10 to 15 seconds

Sources Phase 2 trial (NEJM) New England Journal of Medicine TRIUMPH-4 results Eli Lilly Investor Relations JAMA coverage of Phase 2 results JAMA Related reading Retatrutide Phase 3 Trials 2026: TRIUMPH & TRANSCEND-T2D Tracker Living tracker of every retatrutide trial TRIUMPH-1/3/4/5, TRIUMPH-Outcomes, TRANSCEND-T2D-1/2, and SYNERGY-OUTCOMES Phase 3 readouts

After completing dose titration over 16 weeks, patients transition to a once-weekly 2.4mg injection for ongoing weight maintenance

Your healthcare provider at TrimRx, or your personal doctor, is your best resource for personalized advice

Concerning (Seek medical evaluation) Tachycardia: A resting heart rate consistently over 100 bpm

In a systematic review of 55 double-blinded, placebo-controlled randomized clinical trials, GLP-1RA treatment was associated with an increased risk of cholelithiasis compared with placebo (RR 1.46, 95% CI 1.091.97) but not cholecystitis, cholangitis, or pancreatitis (63)