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Significant effects of HM11260C (efpeglenatide) on body weight over 20 weeks in obese subjects without diabetes: a randomised, double-blind, placebo controlled study [abstract]

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Fauconnier J, Lanner JT, Zhang SJ, et al

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GLP-1R-agonists regulate several inflammatory pathways, including cytokine production, oxidative stress, glucotoxicity, lypotoxicity and the recruitment of immune cells in several organs

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However, challenges such as gastrointestinal side effects and high medication costs are limiting broader accessibility

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Patients with diabetes already face elevated pancreatitis risk due to obesity, hypertriglyceridemia, and metabolic syndromeconditions common among those prescribed GLP-1 medications

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rhamnosus GG (Keystone Postbiotic) This unique postbiotic combination increases butyrate, a short-chain fatty acid that directly stimulates GLP-1 receptors and helps extend feelings of fullness and improve metabolic control

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