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Cell culture and transfection HEK293T cells (ATCC) were maintained in DMEM medium (Thermo Fisher Scientific, C11995500BT) supplemented with 10% fetal bovine serum (Thermo Fisher Scientific, 10099141) at 37 C, 5% CO 2

These actions help improve glycaemic control in people with type 2 diabetes

At the 50% interim analysis (60 patients), in the ITT analysis the rate of clinically significant RGV was 25.0% in the continue group and 3.1% in the hold group (absolute difference, 21.9% [90% CI, 7.0%-36.7%]

Primary bile acids are synthesized in hepatocytes and are transformed to secondary bile acids in the intestine by gut bacteria

Your choice should balance two competing needs: measurable volumes for your smallest planned dose, and single-draw capability for your largest planned dose

doi: 10.1016/j.jacc.2024.06.016