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In a study using cultured rat hippocampal neurons, pre-treatment of nerve cells with GLP-1 resulted in a weakened Ca 2+ response to glutamate and weakened membrane depolarization ( Effects on Parkinsons Disease Parkinsons disease (PD) is a chronic neurodegenerative disease that affects the central nervous system and the second most common neurodegenerative disease after AD (56)

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doi: 10.3389/fphar.2020.00356 [DOI] [PMC free article] [PubMed] [Google Scholar] 89

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Soon after developing GLP-1s, researchers uncovered a second therapeutic effect that could benefit an even larger patient population: sustainable, clinically meaningful weight loss

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Hair loss, joint pain, back pain, and depression werent reported in studies of the drug

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