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According to Sarwer and Maccarone, scientists believe these shifts in mood are caused by how the drug changes the brain's central reward pathways by diminishing responses to the neurotransmitter dopamine

The companys new chief executive, Luke Miels, who took over from Emma Walmsley at the start of the year, reiterated its 40bn-plus sales target by 2031

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Comparison of clinical efficacy and safety of weekly glucagon-like peptide-1 receptor agonists dulaglutide and semaglutide in Japanese patients with type 2 diabetes: randomized, parallel-group, multicentre, open-label trial (COMING study)