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NHE3 plays an important role in reabsorbing filtered Na + in the proximal tubules (Schultheis et al., 1998)

Caution Despite its strengths including a large sample size and propensity matching this is an observational study that is subject to confounders and bias

Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and lower gut

I was somewhat surprised to see this as a long-term complication with patients continuing to experience problems even after stopping the medication, Ali said

10.1186/s12933-017-0646-z 48 LeporeJ

However, controversy exists regarding whether these effects are mediated through the direct effects of GLP-1RA targeting intrahepatic cells