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Berberine is an isoquinoline alkaloid found in the roots and rhizomes of various medicinal plants, with an extensive history for managing type 2 diabetes [5]

### Funding Statement SDL and AC were supported by the National Science Foundation (Grant Nos.\ CAREER DMS-1944574 and DMS-2325258) ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained

Triage safety using the contraindications and red flag screens, then route the file to provider review

Take directly into the mouth, or by adding water or juice

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Insurance coverage for GLP-1 medications remains selective, but proven appeal strategies and affordable compounded options can help you access treatment today without delays