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doi: 10.2337/dci24-0003
For most patients, the demonstrated benefits substantially outweigh known risks
Specifically, the study fixed 12 conserved residues from known GLP-1RAs and used ProteinMPNN to generate 10,000 novel sequences
Hence, no consistent data on differences in adherence between short- and long-acting GLP-1 RAs could be found
Some participants may have been reluctant to report poor adherence to maintain social desirability
