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That figure is contested: a 2026 Cell Reports Medicine analysis found no disproportionate muscle loss, with relative muscle improving

According to NICE guidelines (NG28), GLP-1 receptor agonists may be considered for type 2 diabetes when metformin and other treatments have not achieved glycaemic targets

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Absence of evidence is not evidence of absence

As lifestyle changes, sedentary behavior, and unhealthy dietary patterns become increasingly common, the incidence of these metabolic disorders continues to surge