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Abbreviations GLP-1: Glucagon-like peptide-1 GLP-1RA: Glucagon-like peptide-1 receptor agonist T2DM: Type-2 diabetes mellitus DPP-4: Dipeptidyl peptidase 4 HbA1c: Hemoglobin A1c NASH: Non-alcoholic steatohepatitis NAFLD: Non-alcoholic fatty liver disease Camp: Cyclic adenosine monophosphate PKA: Protein kinase A EPAC: Exchange protein directly activated by cAMP PI3K: Phosphoinositide 3-kinase PYY: Peptide YY CCK: Cholecystokinin GLUT4: Glucose transporter type 4 mTORC1: Mammalian target of rapamycin complex 1 References Ahrn B (2015) Hepato-incretin function of GLP-1: novel concept and target in type 1 diabetes

Week 3 Rep range went to pyramids sets of 5 went to 15, 12, 10, 8, 6, Week 4 Was a test to see how much strength I had gained, I went back to the first cycle of rep range of 6

once opened, they typically retain potency for 2830 days under proper refrigeration conditions

Cost varies: branded Ozempic/Wegovy averages $900$1,400/month without insurance

The retatrutide dosage chart provides detailed reference information for the various titration schedules used across different clinical trials

doi:10.1016/S0140-6736(12)61267-7 19