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Similarly, bezafibrate, a peroxisome proliferator-activated receptor alpha (PPAR) agonist, has been shown to suppress inflammation and oxidative stress, thereby alleviating diabetic spermatogenesis disorder (95)

doi: 10.1002/oby.23596, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 38

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

Large cardiovascular outcome trials consistently show fewer heart attacks and strokes with GLP-1 use

This is especially important for anyone with cardiovascular disease, type 2 diabetes, thyroid conditions, a history of pancreatitis, or those taking multiple medications

After all, there are over 100 originator drugs and almost as many biosimilars in the pipeline, many of which will never progress to commercialisation, but some of which will further push the boundaries on patient convenience, efficacy and indication spectrum
