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Potential explanations include differences in the type of patients included, adherence to study treatment, sample size, duration of drug exposure, and GLP1 receptor activation with greater HbA1c reduction with longer-acting human GLP1-based analogs than with some short-acting exendin-4 analogs

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doi: 10.1056/NEJMoa1509225 [DOI] [PubMed] [Google Scholar] 251