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doi: 10.2337/dc20-1622

All patients prescribed an SGLT-2 inhibitor should be cautioned on the possibility of euglycaemic ketoacidosis, a rare complication that may occur if patients are fasting or have an intercurrent illness

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Failure of Lifestyle Monotherapy Lifestyle modification (LSM) is foundational but often insufficient for long-term weight maintenance in Class II or III obesity: Timing: Patients with a history of weight cycling (yo-yo dieting) are unlikely to achieve sustained success through behavioral interventions alone