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As a board-certified family physician and aesthetic expert with specialized training in obesity medicine, Dr

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Accessed March 9, 2026.

Even though most of these drugs do not cross the blood-brain barrier, brain fog is often one of the first symptoms affected and may be due to improvements in blood flows

19,20 From the current recommendation, pioglitazone has been established in both diabetic and nondiabetic MAFLD patients with significant fibrosis (F2), whereas vitamin E is recommended in nondiabetic MAFLD patients with F2 non-cirrhosis