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Brand-name medications like Mounjaro and Zepbound are FDA-approved

Compounded tirzepatide may be prescribed when appropriate based on individual evaluation and availability

This initial dose serves primarily as a tolerability step, allowing your body to adjust before dose escalation to 5 mg and potentially higher doses based on therapeutic goals and side effect tolerance

Other data show the medications support nerve repair in conditions like multiple sclerosis (MS)

Two further Phase 3 trials are due to report later in 2026

When to switch from semaglutide to tirzepatide Potential side effects When switching medications, you may experience a few side effects such as nausea, abdominal pain, indigestion, diarrhea, constipation, and gastrointestinal problems