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Given the documented effects of GLP-1 and GLP-2 on rodent liver regeneration and their routine therapeutic targeting for other indications, we sought to explore perioperative dynamics of GLP-1 and GLP-2 in patients undergoing hepatic resections

Semaglutide and liraglutide are GLP-1RAs, while tirzepatide is a dual GLP-1/gastric inhibitory polypeptide co-agonist

They can protect lean body mass and micronutrient status during weight loss (which is often rapid with GLP-1s)

Most of the developed pharmacokinetic models were population pharmacokinetic models utilizing nonlinear mixed effect modeling (22 of 30)

[(accessed on 7 January 2026)];2022 Available online: 83.Eli Lilly Company Zepbound (Tirzepatide) Injection for Subcutaneous Use, U.S

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