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For example, in a study from the Journal of the American Medical Association , patients achieved around 5.9% loss of their total body weight in three months

Additionally, the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity trial demonstrated that semaglutide consistently reduced major cardiovascular event endpoints by approximately 20% compared to placebo over an approximately 3-year follow-up period in patients with overweight or obesity and cardiovascular disease (Table 1), but without diabetes [93]

Samms RJ, Sloop KW, Gribble FM, Reimann F, Adriaenssens AE

Journal of psychosomatic research , 69 (1), 33-41

Anhedonia in adolescents at transdiagnostic familial risk for severe mental illness: Clustering by symptoms and mechanisms of associations with behavior

Products marketed as "GLP-1 patches" do not contain GLP-1 receptor agonists regardless of marketing terminology