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51 However, subdiaphragmatic vagotomy had no effect on GLP-1-induced acute activation of PKA in the brain, indicating that the vagus nerve is not involved in GLP-1RAs entering the brain

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Randomization was stratified by baseline fibrosis stage (F2 vs
doi: 10.1021/bi010902s
Higher-risk groups include older adults, those following vegetarian or vegan diets, patients taking metformin or long-term proton pump inhibitors, and individuals with a history of gastrointestinal surgery or conditions such as pernicious anaemia or coeliac disease
