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For example, prescribing data for one oral GLP-1 tablet reported that among patients who had gastrointestinal side effects, 60% were mild, 36% were moderate and 4% were severe

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All the participants provided written informed consent to participate in this study

If tirzepatide proves effective, it might offer an alternative or complementary approach, particularly for individuals who have not responded adequately to standard treatments or who have co-occurring metabolic conditions

We report herein a series of pharmacological and molecular studies in two validated mouse models of PCOS, generated by gestational (PNA) or postweaning (PWA) androgenization, addressing the effects of GLP1-based multi-agonist therapies on metabolic and reproductive traits of PCOS

4 (see Supplementary Material, Table S5E)