what is the difference between dpp-4 inhibitors and glp-1 analogs receptor agonists or inhibitors: How to guide clinician? what is the difference between

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doi: 10.1007/s00125-015-3754-x

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Researchers looked at 37.1 million adults with type 2 diabetes across this dataset and found a modest increase in the risk of NAION among individuals with [type 2 diabetes] associated with semaglutide use. A study published in June 2025 also connected GLP-1 RAs to neovascular age-related macular degeneration (nAMD)

February 2024

Access and Convenience Differences Traditional in-person care: Requires scheduling appointments during office hours Travel time to and from appointments Waiting room time Face-to-face interaction with providers Physical examination capability Immediate emergency intervention if needed during visits Zealthy telehealth care: Asynchronous messaging (respond when convenient) No travel or waiting room time Video or phone visits available for more complex discussions 24/7 message submission (responses typically within 48 hours on business days) Limited physical examination capability Emergency situations require you to seek local care independently Oversight and Coordination Differences Traditional in-person care: Provider likely has access to your complete medical record Can coordinate with your other healthcare providers more easily Physical examination at each visit In-person vital sign monitoring (blood pressure, heart rate) Ability to order labs and review results in integrated systems Zealthy telehealth care: Limited to information you provide through intake forms and messaging You're responsible for coordinating between Zealthy providers and your primary care team No physical examination capability You may need to arrange separate lab work if recommended Relies on self-reported data for monitoring Neither approach is inherently "better"-they serve different needs