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Description
Adding prandial GLP-1 receptor agonists to basal insulin: a promising option for type 2 diabetes therapy
Regardless of which form of semaglutide you choose, you can expect significant improvements in weight loss and glycemic control
This dual modulator is able to activate GPR119 (EC 50 : 0.95 M, 81.5% activity of AR231453 @1 M) and inhibit DPP4 (IC 50 : 0.22 M) in vitro
Although retinal thickness was generally reduced, visual acuity results were less consistent (123)
doi: 10.1210/jc.2008-1641
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