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Researchers exploring adaptive capacity and peptide mapping may find this concept particularly interesting

(2007) doi:10.1016/j.clinbiochem.2007.02.006

It does not mean the medication is ineffective for weight loss, and the symptom typically resolves on its own

Monteiro, M

As an example, the combination of GLP1RA liraglutide with metformin in infertile obese PCOS patients increased the pregnancy rate after IVF treatment compared to metformin treatment alone although weight loss was similar in these groups, 52 supporting the hypothesis of endometrium as an effective target for GLP1RA therapy

We did, however, observe a 5.4 mmol/mol (0.5%) reduction in HbA 1c in the GLP-1 RA cohort, similar to reports from randomised controlled trials [45, 46]
