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Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling

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Glucagon-like peptide-1 (GLP-1) receptor agonists have transformed the management of type 2 diabetes and obesity, offering significant benefits in glycemic control and weight reduction

Resources We Trust Cleveland Clinic: This Is How to Lose Weight the Right Way and Keep It Off Johns Hopkins Medicine: Maintaining Weight Loss Massachusetts General Hospital: Fitness for People Taking GLP-1 Agonists: A Comprehensive Guide WashU Medicine: Stopping GLP-1 Drugs Can Quickly Erase Cardiovascular Benefits Yale School of Medicine: What Is the Impact of GLP-1s in Older Adults With Obesity