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In the SURPASS 2 trial, Tirzepatide, at all doses (5mg, 10mg and 15mg) was more effective at lowering Hba1c and blood glucose levels compared to Semaglutide 1mg, aka Ozempic
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These include methadone, buprenorphine, and extended-release naltrexone for opioid use disorder

The implication is that GLP-1 agonists may actively decrease the risk of cachexia in cancer by mitigating the associated inflammatory environment

Glucagon-like peptide-1 receptor agonists (GLP-1RAs), currently approved for the treatment of type 2 diabetes mellitus, obesity, and obstructive sleep apnea, have recently emerged as potential new pharmacotherapies for ASUDs

Microdosing option: Some people split their weekly dose into smaller, more frequent injections (e.g., 4mg twice weekly instead of 8mg once weekly) to reduce GI side effects
