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A second study investigated delivery of GLP-1 in a SOD1 G93A mouse model using an intracerebroventricular injection of mesenchymal stem cells (MSC) stably transfected to secrete GLP-1 21

This finding aligns with evidence from large trials in T2DMsuch as LEADER, REWIND, and AMPLITUDE-Owhich reported death reductions ranging from 12 to 22% [10, 22]

doi: 10.1016/j.cct.2024.107516 [DOI] [PMC free article] [PubMed] [Google Scholar] 203.Malhotra A, Grunstein RR, Fietze I, et al

adults would meet SELECT trial eligibility criteria

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