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This theory posits that excessive wantinga heightened motivational drive triggered by reward-related cuesunderlies addictive behaviors, distinct from the hedonic liking of drugs

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Tirzepatide has received approval for use in patients with T2D following several phase 3 studies testing and demonstrating its marked anti-hyperglycemic efficacy and positive actions on multiple cardiovascular risk factors, associated with an excellent safety profile [2, 3]

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3 The role of GLP-1/GLP-R axis in related signal pathways GLP-1 is known to increase insulin secretion by cells under hyperglycemic conditions