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The before photo often represents someone at their heaviest weight after months or years of progressive gain

The potential of semaglutide once-weekly in patients without type 2 diabetes with weight regain or insufficient weight loss after bariatric surgerya retrospective analysis

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N Engl J Med 2024

It is a single-chain, fatty-acid-modified peptide engineered to engage both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor