empower glp-1 GLP‑1 Nutrition Mastery Certificate – Enroll Online Today GLP-1 medications: Transforming health and

significant weight reduction (~ 710%) through calorie restriction, with or without exercise, and bariatric/metabolic surgery results in high turnover bone loss

Yet medicine rarely gives benefit without trade-offs

Nature 546 , 259264 (2017)

Mechanism of Action Simplified: Injury/Inflammation \rightarrow Phospholipase A_2 \rightarrow Arachidonic Acid \rightarrow COX-1/COX-2

These companies (Eli Lilly and Novo Nordisk) also announced plans to lower direct-to-consumer prices as part of a deal with the Trump administration

Beta-Blockers Mechanism: Block 1 receptors heart rate & contractility cardiac output Examples: Metoprolol, Atenolol, Carvedilol (+ blocker) Key Points: Useful in hypertension with angina, post-MI, or heart failure Caution: Asthma (non-selective -blockers), diabetes (may mask hypoglycemia) 3