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10.3233/adr-240053 J

Why "Wegovy Face" Happens And the Science of Preventing It One of the most-searched phrases of 2026 is "Wegovy face" the hollow, deflated, prematurely-aged facial appearance some patients develop after rapid semaglutide-induced weight loss

Clinical data suggests average weight reductions range from 510% of baseline body weight over 1620 weeks at therapeutic doses

A second patient, a 29-year-old woman with established diagnosis of IIH, presented for evaluation of worsening headache and occasional graying out of vision with discontinuation of acetazolamide and weight gain of 15 pounds

This is a major practical advantage

As with any prescription medication, whether a GLP-1 is appropriate depends on your individual health history and goals
