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The FDA approved it on April 1, 2026, and Lilly launched on April 6

The same active ingredient in Ozempic (semaglutide) is now licensed specifically for weight management under the brand name Wegovy at a higher dose

Tumor necrosis factor is a therapeutic target in several diseases and anti-TNF treatment is successfully applied in rheumatoid arthritis, psoriasis, ankylosing spondylitis, and IBD

[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Beernink J.M., van Mil D., Laverman G.D., Heerspink H.J.L., Gansevoort R.T

While medications like semaglutide focus on a single pathway that helps control appetite and blood sugar, tirzepatide activates two complementary pathways at the same time