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In both mice and rats, administration of ICV exendin-4(939) (Ex9), a potent GLP-1r antagonist, during oral glucose impairs glucose tolerance and reduces insulin levels (104, 209, 229)

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Patients taking GLP-1 receptor agonists should have regular cardiovascular check-ups to ensure their safety and achieve the best possible outcomes

Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines

References Bailey RA, Wang Y, Zhu V, Rupnow MFT

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