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GLP-1 Analogs can have a number of benefits, including: Significant weight reduction when combined with diet and exercise Improved blood sugar control Reduced risk of major cardiovascular events Health benefits like improved blood pressure and cholesterol levels In the Semaglutide Treatment Effect in People with Obesity (STEP) study, published in The New England Journal of Medicine , participants receiving the once-weekly semaglutide lost an average of 34 pounds over 68 weeks, showcasing its effectiveness in managing obesity

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2 There is a theoretical risk of medullary carcinoma of the thyroid due to the GLP-1-mediated effect of calcitonin release

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