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Xiao G, Zhu S, Xiao X, et al

This contrasts sharply with prescription GLP-1 agonists, which demonstrate 10-22 percent average weight loss in Phase 3 randomized controlled trials

GLP-1s and Endurance Performance: What Athletes Need to Know Dec 10, 2025 GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) have quickly gained attention for their dramatic effects on weight loss and appetite control

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Studies indicate that people taking Wegovy can lose a significant percentage of their initial body weight

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