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4 Other GLP-1RA approved by the US FDA for the treatment of T2DM include liraglutide (Victoza, 2010), exenatide extended-release (Bydureon, 2012), albiglutide (Tanzeum, 2014), and dulaglutide (Trulicity, 2014)

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The availability of oral semaglutide may help to broaden treatment options and facilitate the adoption of earlier treatment with arGLP-1 in the management of DM2

There is a complex interaction between host genetic and metabolic makeup, diet, and microbiota (Figure 5)

Zepbound (tirzepatide) is a prescription medication approved by the FDA for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbid condition