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However, exposure to high glucose conditions did increase mRNA expression and membrane-bound DPP-4 activity in human glomerular (76) and dermal (77) microvascular endothelial cells in vitro , although, interestingly, not in macrovascular (human aortic) endothelial cells (77)
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In a pancreas perfusion study, EX4 significantly stimulated glucagon secretion in diabetic rats but not normal rats
P9 strongly induces IL-6 expression, which in turn dose-dependently increases GLP-1 secretion from L cells
Schedule per drug from prescribing information Optionally filter to a user-specified target dose if lower than the label maximum
