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Large trials have demonstrated that these agents reduce cardiovascular events in patients with cardiovascular disease and improve outcomes in heart failure, kidney disease and metabolic dysfunction-associated steatohepatitis

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HR, 1.89 [CI 1.02 to 3.51]), and loperamide 2.1% vs

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Through its extensive connections with limbic and cortical structures, this interoceptive stream also shapes emotional states, guides decision-making, modulates stress responses, and even contributes to memory consolidation