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Doctors, politicians and drugmakers quickly criticized the company for not disclosing the risks associated with the compounded drugs that Hims & Hers sometimes uses for weight loss
doi: 10.1016/S0140-6736(21)01324-6 Summary Keywords glucagon, GLP-1, obesity, co-agonist, weight loss Citation Hope DCD, Vincent ML and Tan TMM (2021) Striking the Balance: GLP-1/Glucagon Co-Agonism as a Treatment Strategy for Obesity

The path of metabolic peptide development is a story of compounding synergy

The combination is generally well-tolerated, though both medications can cause GI side effects

ACS Chem Biol 18 : 756771

While both medications reduce food intake, Tirzepatide often shows superior hunger control in clinical studies due to its dual-action mechanism
