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Yes, but dosing may need adjustment with insulin or sulfonylureas

Acknowledgements We would like to thank all the participants, investigators, and trial-site staff

[41] This trial's event-driven design and focus on high-risk patients underscored semaglutide's cardiovascular benefits, influencing regulatory decisions despite the retinopathy findings

However, surgery may be needed if it does not resolve within a week or investigations show worsening obstructive features

If resting heart rate rises substantially above baseline or exceeds 100 beats per minute at rest, further evaluation may be appropriate

In a pooled analysis of semaglutide trials, confirmed pancreatitis occurred in 0.1% of semaglutide-treated patients versus 0.1% of placebo patients, but individual susceptibility varies [9]