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This scenario leads to an increase in oxidative stress (OS), which is related to mitochondrial dysfunction, accumulations of protein and oxidated lipids, and an impairment of the antioxidant system [64,65,66,67,68,69,70]

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41864196, 10.2337/db14-0849 [DOI] [PubMed] 19.McElroy SL, Mori N, Guerdjikova AI, Keck PEJ (Feb

This increases cancer risk by two distinct mechanisms both through the promotion of chronic inflammation, and through inhibition of the acute inflammation that is important to halt tumorigenesis (anti-tumor immunity)

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