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From study baseline to the end of follow-up, GLP-1RAs treatment resulted in statistically significant decreases in weight (MD=-2.32 kg, 95% CI: -4.21 to -0.43) and BMI (MD=-0.82 kg/m2, 95% CI: -1.47 to -0.17)

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More recent evidence is expanding their benefits to heart failure with preserved ejection fraction and clinically important renal outcomes in patients with and without diabetes