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To further investigate why these three missense mutations led to a significantly increased GLP-1R ECD affinity of semaglutide mutant 524, a comprehensive structural biophysical analysis [50] was conducted for the 10000 structural models built by Modeller [44] with a structural electrostatic perspective

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Also in February 2025, the FDA approved GSK Biologicals Penmenvy vaccine for active immunisation against invasive disease caused by Neisseria meningitidis serogroups A, B, C, W and Y in individuals aged 10-25 years

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